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Locul cercetării clinice şi epidemiologice în sistemul CDI
Alexandru Dan Corlan,
Revista de Politica Ştiinţei şi Scientometrie 3(1):43-54, 2014
ABSTRACT
Clinical/epidemiologic research (CER) provides the
basis of allopathic (mainstream) medicine by supplying the
predictive theories needed for medical practice and health policy
making. These theories consist of laws to probabilistically predict
future clinical events based on current and previous
measurements. CER studies consist of observations and experiments
performed on patients, toghether with their theoretical
interpretation. They are complemented by pathology, farmacokinetics
and signal studies that are also performed in patients, but explore
the relations between measurables rather than clinical
events. Purely theoretical studies include metaanalyses—that are
statistical analyses of data pooled from multiple similar studies,
and more recently population pharmacokinetic and pharmacometric
studies. The structure of the CER subsystems in developed countries
is similar, and includes medical schools, teaching (and research)
hospitals, epidemic surveillance government institutions, agencies
such as the Food and Drug Administration, and a segment of the
industry that organises clinical research for the purpose of testing
and characterisation of drugs, devices and diagnostic and
therapeutic machinery. The performance of the CER subsystem is
essential for the proper training of physicians and for the
atractivity of the health system for professional elites. The CER
subsystem, estimated by a variety of metrics, such as the proportion
of employees, funds and number of publications, represents about
6–11% from the overall research system in Romania, compared about
18–31% in the USA.
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